NEUROMUSCULAR AND VAGAL BLOCKING ACTIONS OF PANCURONIUM BROMIDE, ITS METABOLITES, AND VECURONIUM BROMIDE (ORG NC 45)AND ITS POTENTIAL METABOLITES IN THE ANAESTHETIZED CAT
نویسندگان
چکیده
منابع مشابه
Comparison of the neuromuscular blocking properties of ORG NC 45 and pancuronium in the rat, cat and rhesus monkey.
The neuromuscular and cardiovascular activities of pancuronium were compared with those of its 16(3 monoquaternary congener, Org NC 45, in the anaesthetized rat, cat and rhesus monkey. In the rat Org NC 45 was 3.4 times less potent as a neuromuscular blocking agent than was pancuronium. In the cat, both drugs were found to be approximately equally eliminated by the liver, whereas renal eliminat...
متن کاملAntagonism of org NC 45 (vecuronium) and pancuronium neuromuscular blockade by neostigmine.
The antagonism, by neostigmine, of neuromuscular blockade produced by either Org NC 45 or pancuronium was studied in 29 anaesthetized patients during a continuous infusion of the myoneural blocker. The ED50 of neostigmine (dose which produced a 50% antagonism) when antagonizing Org NC 45 and pancuronium was 0.011 mg kg-1 and 0.010 mg kg-1 respectively. The dose-response relationships for the an...
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این پژوهش با هدف "بررسی وضعیت موجود آموزش عالی مجازی در ایران و راههای توسعه و ارتقای آن " و با روش توصیفی-تحلیلی و پیمایشی صورت پذیرفته است. بررسی اسنادو مدارک موجود در زمینه آموزش مجازی نشان داد تعداد دانشجویان و مقاطع تحصیلی و رشته محل های دوره های الکترونیکی چندان مطلوب نبوده و از نظر کیفی نیز وضعیت شاخص خدمات آموزشی اساتید و وضعیت شبکه اینترنت در محیط آموزش مجازی نامطلوب است.
Neuromuscular blocking and autonomic effects of vecuronium and atracurium in the anaesthetized cat.
The effects of vecuronium and atracurium on neuromuscular transmission, on the responses of the heart rate to vagal stimulation and on the responses to preganglionic stimulation of the nictitating membrane were compared in the chloralose-anaesthetized cat. Vecuronium was four times more potent than atracurium as a neuromuscular blocking agent, whereas the two compounds had similar potencies in ...
متن کاملRocuronium Bromide Versus Vecuronium Bromide
BACKGROUND: Rocuronium Bromide is a newer, low potency nondepolarising neuromuscular blocking agent. It is proven to be five to seven times less potent than vecuronium.The aim of the present study was to evaluate the effectiveness of 2ED95 (2 times effective dose 95) dose (0.6mg/kg) of rocuronium with regard to onset time, the intubating conditions and the duration of action and to compare it w...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1983
ISSN: 0007-0912
DOI: 10.1093/bja/55.8.703